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Cat Number: API923288953

Nilotinib hydrochloride

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APIs
Standard Qualification
CP/EP/USP/In-house; Facility GMP DMF/CEP/EMA
CAS Number
923288-95-3
Synonyms
AMN-107 HCl
Description
Nilotinib hydrochloride(AMN-107 HCl) is an orally available Bcr-Abl tyrosine kinase inhibitor with antitumor activity for modulation of neuroinflammation and cognitive deficits, and may be used in studies of chronic myelogenous leukemia.
Molecular Formula
C28H23ClF3N7O
Molecular Weight
565.98
Smiles
Cl.O=C(NC=1C=C(C=C(C1)C(F)(F)F)N2C=NC(=C2)C)C3=CC=C(C(=C3)NC=4N=CC=C(N4)C5=CN=CC=C5)C
Purity
1
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
DMSO: 90 mg/ml (159.02 mM)Ethanol: 1 mg/ml (1.77 mM)
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