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Cat Number: API59461

Procaine

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APIs
CAS Number
59-46-1
Description
Procaine is a local anesthetic drug of the amino ester group, which acts through multiple targets.
MolecularWeight
236.31
MolecularFormula
C13H20N2O2
SMILEs
CCN(CC)CCOC(=O)C1=CC=C(C=C1)N
Appearance
Crystalline powder
Solubility
Soluble in water (1 g/200ml), ether, benzene, chloroform, ethanol, ethyl ether, alcohol, and water (9.45X10+3 mg/l at 30℃).
Storage
Store at 4℃
MeltingPoint
61ºC
BoilingPoint
373.6±22.0 ℃ at 760 mmHg
Density
1.1±0.1 g/cm3
RefractiveIndex
1.543
IC50
Sodium channel protein type III alpha subunit: IC50 = 110 µM (human); Sodium channel protein type VIII alpha subunit: IC50 = 110 µM (human); Sodium channel protein type II alpha subunit: IC50 = 110 µM (human); Sodium channel protein type I alpha subunit: IC50 = 110 µM (human)
pKValue
pKa= 8.05 @ 15 deg C, pKb= 9.24 (Predicted)
FlashPoint
179.8±22.3 ℃
VapourPressure
0.0±0.8 mmHg at 25℃
PreparationUse
a local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block.
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