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Cat Number: API486460326

Sitagliptin

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APIs
CAS Number
486460-32-6
Description
Sitagliptin (MK0431), a new oral hypoglycemic (anti-diabetic drug), is a new dipeptidyl peptidase-4 (DPP-4) inhibitor. This enzyme-inhibiting drug is used either alone or in combination with metformin or thiazolidinedione for treatment of type 2 diabetes mellitus.
Molecular Formula
C16H15F6N5O
Molecular Weight
407.31
Smiles
N[C@@H](CC(=O)N1CCN2C(C1)NNC2C(F)(F)F)CC1CC(F)C(F)CC1F
Purity
0.994
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
DMSO: 16.67 mg/mL (40.92 mM)H2O: ＜1 mg/mL (Insoluble)
Relative Density
1.614
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